Index to Chiropractic Literature
Index to Chiropractic Literature
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Friday, September 20, 2019
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ID 25338
  Title The importance of vitamin D in autoimmune conditions
URL
Journal Nutr Perspect. 2018 Oct ;41(4):24-25
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Peer Review No
Publication Type Article
Abstract/Notes

Vitamin D is one of the essential nutrients to sustain human health.  As a member of the steroid hormone family, it has a classic role in regulating metabolism of calcium and a non-classic role in affecting cell proliferation and differentiation.  Epidemiological studies have shown that 25OHD deficiency is closely associated with common chronic diseases such as bone metabolic disorders, tumors, cardiovascular diseases, and diabetes.  25OHD deficiency is also a risk factor for neuropsychiatric disorders and autoimmune diseases.  Vitaman D immunomodulatory effects are suppression of adaptive immunity through a reduction in the production of interleukin (IL)-2, gamma interferon, and tumor necrosis factor, inhibition of expression of ILl-6, secretion and procudtion of autoantibodies by B lymphocytes, and activation of innate immunity.

This abstract is reproduced with the permission of the publisher. Full text is available with membership in the American Chiropractic Association, Council on Nutrition, or through CINAHL (EBSCOhost).


 

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