Index to Chiropractic Literature
Index to Chiropractic Literature
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ID 25250
  Title Association between utilization of chiropractic services for treatment of low back pain and risk of adverse drug events
URL https://www.jmptonline.org/article/S0161-4754(17)30136-7/fulltext
Journal J Manipulative Physiol Ther. 2018 Jun;41(5):383-388
Author(s)
Subject(s)
Peer Review Yes
Publication Type Article
Abstract/Notes

Objectives: Mortality rates due to adverse drug events (ADEs) are escalating in the United States. Analgesics are among the drug classes most often associated with occurrence of an ADE. Utilization of nonpharmacologic chiropractic services for treatment of low back pain could lead to reduced risk of an ADE. The objective of this investigation was to evaluate the association between utilization of chiropractic services and likelihood of an ADE.

Methods: We employed a retrospective cohort design to analyze health insurance claims data from the state of New Hampshire. After inversely weighting each participant by their propensity to be in their cohort, we employed logistic regression to compare recipients of chiropractic services to nonrecipients with regard to likelihood of occurrence of an ADE in an outpatient setting.

Results: The risk of an ADE was significantly lower among recipients of chiropractic services as compared with nonrecipients. The adjusted likelihood of an ADE occurring in an outpatient setting within 12 months was 51% lower among recipients of chiropractic services as compared to nonrecipients (OR 0.49; P = .0002). The reported ADEs were nonspecific with regard to drug category in the majority of incidents that occurred in both cohorts.

Conclusions: Among New Hampshire adults with office visits for low back pain, the adjusted likelihood of an ADE was significantly lower for recipients of chiropractic services as compared to nonrecipients. No causal relationship was established between utilization of chiropractic care and risk of an ADE. Future research should employ larger databases, rigorous methods to reduce risk of bias, and more sensitive means of identifying ADEs.

Author keywords: Chiropractic, Low Back Pain, Adverse Drug Event, Adverse Drug Reaction

Author affiliations: JMW, AWJT: Health Services Research, Southern California University of Health Sciences, Whittier, California; JMG, LAK: Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire

This abstract is reproduced with the permission of the publisher; full text is available for free at the publisher's site. PubMed Record


 

 

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