• Taylor JA
• Green-Deslauriers K
• Tanaka DI

• Ehlers-Danlos Syndrome / therapy
• Joint Instability

Two cases of Ehlers-Danlos Syndrome (EDS) are discussed. The first case illustrates some of the classic findings and complications often seen in this rare, inherited, connective tissue disorder. The second case illustrates a much less severe presentation in which the diagnosis of Ehlers-Danlos syndrome is equivocal. A review of the pertinent literature offers an understanding of the pathophysiology, clinical presentation, radiological findings, differential diagnosis and complications of this condition. It is essential for practitioners to understand the indications and contraindications for various treatment and diagnostic procedures such as angiography, surgery and joint manipulation. Due to the severity of potential complications to the skin, bones, joints, cardiovascular, visceral and ocular structures, accurate diagnosis is essential.

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