Lower-back pain is usually benign and self-limiting, but this may not be true among patients with concomitant lower-extremity symptoms. A strong determinant of disability associated with lower-back pain is the presence of a symptomatic leg.1 Part 1 of this article presented an evidence-based algorithm to provide clinicians with a systematic, data-driven approach for the diagnostic work-up of worrisome leg symptoms that are vascular in origin. Part 2 uses the current scientific literature to present a practical, evidence-based approach to the diagnostic evaluation of worrisome lower-extremity symptoms with a neuropathic radicular origin.
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