Index to Chiropractic Literature
Index to Chiropractic Literature
My ICL     Sign In
Wednesday, December 1, 2021
Index to Chiropractic LiteratureIndex to Chiropractic LiteratureIndex to Chiropractic Literature

For best results switch to Advanced Search.
Article Detail
Return to Search Results
ID 22542
  Title The effect of spinal manipulative therapy on experimentally induced pain: A systematic literature review [review]
Journal Chiropr & Manual Ther. 2012 ;20(26):Online access only 52 p
Peer Review Yes
Publication Type Review

Background: Although there is evidence that spinal manipulative therapy (SMT) can reduce pain, the mechanisms involved are not well established. There is a need to review the scientific literature to establish the evidence-base for the reduction of pain following SMT.

Objectives:To determine if SMT can reduce experimentally induced pain, and if so, if the effect is only i) at the level of the treated spinal segment, ii) broader but in the same general region as SMT is performed, or iii) systemic.

Design: A systematic critical literature review.

Methods: A systematic search was performed for experimental studies on healthy volunteers and people without chronic syndromes, in which the immediate effect of SMT was tested. Articles selected were reviewed blindly by two authors. A summary quality score was calculated to indicate level of manuscript quality. Outcome was considered positive if the pain-reducing effect was statistically significant. Separate evidence tables were constructed with information relevant to each research question. Results were interpreted taking into account their manuscript quality.

Results: Twenty-two articles were included, describing 43 experiments, primarily on pain (n = 27) or temperature (n = 9). Their quality was generally moderate. A hypoalgesic effect was shown in 19/27 experiments on pressure pain, in 3/9 on pain produced by temperature and in 6/7 tests on pain induced by other measures. Second pain provoked by temperature seems to respond to SMT but not first pain. Most studies revealed a local or regional hypoalgesic effect whereas a systematic effect was unclear. Manipulation of a "restricted motion segment" ("manipulable lesion") seemed not to be essential to analgesia. In relation to outcome, there was no discernible difference between studies with higher vs. lower quality scores.

Conclusions: These results indicate that SMT has a direct local/regional hypoalgesic effect on experimental pain for some types of stimuli. Further research is needed to determine i) if there is also a systemic effect, ii) the exact mechanisms by which SMT attenuates pain, and iii) whether this response is clinically significant.

This abstract is reproduced with the permission of the publisher; click on the above link for free full text.


   Text (Citation) Tagged (Export) Excel
Email To
HTML Text     Excel

To use this feature you must register a personal account in My ICL. Registration is free! In My ICL you can save your ICL searches in My Searches, and you can save search results in My Collections. Be sure to use the Held Citations feature to collect citations from an entire search session. Read more search tips.

Sign Into Existing My ICL Account    |    Register A New My ICL Account
Search Tips
  • Enclose phrases in "quotation marks".  Examples: "low back pain", "evidence-based"
  • Retrieve all forms of a word with an asterisk*, also called a wildcard or truncation.  Example: chiropract* retrieves chiropractic, chiropractor, chiropractors
  • Register an account in My ICL to save search histories (My Searches) and collections of records (My Collections)
Advanced Search Tips