Index to Chiropractic Literature
Index to Chiropractic Literature
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ID 22259
  Title Agreement and correlation between the self-report Leeds Assessment of Neuropathic Symptoms and Signs and Douleur Neuropathique 4 Questions neuropathic pain screening tools in subjects with low back-related leg pain
Journal J Manipulative Physiol Ther. 2012 Feb;35(2):196-202
Peer Review Yes
Publication Type Article

Objective: The self-report Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and Douleur Neuropathique 4 Questions (DN4) neuropathic pain screening tools have been shown to be reliable, valid, and able to differentiate neuropathic pain from inflammatory or mixed pain syndromes. However, no studies have compared these tools to determine whether their outcomes are similar. This study evaluated agreement and correlation between the S-LANSS and DN4 in the identification of neuropathic pain in subjects with low back–related leg pain.

Methods: This observational study compared S-LANSS and DN4 scores in 45 patients with low back–related leg pain. The S-LANSS and DN4 cutoff scores of 12 and 4, respectively, were used to classify subjects as positive or negative for the presence of neuropathic pain for each screening tool. The κ statistic was used to determine whether there was agreement in classification of neuropathic pain between the 2 screening tools. Pearson correlation coefficient was used to determine correlation between scores of the 2 screening tools.

Results: Neuropathic pain was identified in 15 subjects (33%) using the S-LANSS and in 19 subjects (42%) using the DN4. Agreement on neuropathic pain classification was fair, with a κ value of 0.34. There was moderate to good correlation (r = 0.62; P < .001) between scores obtained from the 2 tools.

Conclusions: The finding of fair agreement suggests that despite the moderate to good correlation between scores, the cutoff points for the classification of neuropathic pain of the 2 tools may not be congruent.

This abstract is reproduced with the permission of the publisher; click on the above link for free full text on publisher's website. PubMed Record


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