Index to Chiropractic Literature
Index to Chiropractic Literature
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ID 21373
Title Inflammatory response following a short-term course of chiropractic treatment in subjects with and without chronic low back pain
URL http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188345/
Journal J Chiropr Med. 2010 Sep;9(3):107-114
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Peer Review Yes
Publication Type Article
Abstract/Notes Objective: Inflammatory markers interleukin-6 (IL-6) and C-reactive protein (CRP) have not been evaluated in response to a short course of lumbar spinal manipulation. The purpose of this study is to observe the responses of inflammatory markers (IL-6 and CRP) after a series of 9 chiropractic spinal manipulations.

Methods: Twenty-one participants were assigned to a treatment or a control group. Only the treatment group received 9 chiropractic interventions. Pre- and postintervention measures were recorded for blood samples for detection of proinflammatory cytokines IL-6 and CRP.

Results: Mediators of inflammation (IL-6 and high-sensitivity CRP) were modified by the intervention received in the treatment group, and the effect size demonstrated a tendency toward the control group values.

Conclusion: A total of 9 chiropractic lower back manipulations caused the mediators of inflammation to present a normalization response in individuals suffering from chronic low back pain.

This abstract is reproduced with the permission of the publisher; full text by subscription.


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