In recent years, there have been two major developments in the management of AS that make earlier
diagnosis possible and offer the hope of alleviating pain and preventing structural changes that result in loss of function. These developments include the use of magnetic resonance imaging (MRI) to visualize the inflammatory changes in the sacroiliac joint and the axial spine, and
the demonstration that tumor necrosis factor (TNF) blocking agents are highly efficacious in reducing spinal inflammation and possibly in slowing radiographic progression.
This review outlines diagnostic strategies that can help identify AS in its earlier stages. Special attention is
focused on treatment advances, including the use of anti-TNF agents, and how these medications have been incorporated into clinical recommendations for daily use.
This abstract is reproduced with the permission of the publisher. Click on the above link for full text.