Index to Chiropractic Literature
Index to Chiropractic Literature
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Tuesday, May 18, 2021
Index to Chiropractic LiteratureIndex to Chiropractic LiteratureIndex to Chiropractic Literature

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ID 19337
  Title Hypothesis: A candidate peptide mediating some of the effects of the chiropractic adjustment [Poster presented at the 1st College of Chiropractors’ Research Conference, 16th June 2006, BMA House, London, UK]
Journal Clin Chiropr. 2006 Dec;9(4):193
Peer Review Yes
Publication Type Meeting Abstract
Abstract/Notes Health benefits beyond increased joint movement have often been claimed for chiropractic adjustments. Here, evidence is presented that muscle stretch, as a consequence of chiropractic adjustments, could promote the maintenance, repair and growth of nerve and muscle.

Time-force analyses show that most chiropractic adjustments are characterised by a high velocity thrust followed by a period of maintained force. This is likely to result in an initial passive stretch of muscle around the joint followed by a longer eccentric stretch. Recently, we found that eccentric muscle stretch is a powerful stimulus for production of a novel splice variant of insulin-like growth factor-1 called MGF that promotes the growth, repair and survival of both nerve and muscle. Eccentric muscle stretch as a result of the chiropractic adjustment could therefore upregulate MGF resulting in local myotrophic and neurotrophic effects. Acknowledgments: Published work supported by the MRC, BBSRC and Wellcome Trust.

This abstract is reproduced with the permission of the publisher. [ICL In Process citation]

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