This manuscript’s purpose was to establish a knowledge base of information related to stroke and the cervical spine vascular structures, from both historical and current perspectives. The scientific biomedical literatures both indexed (ie. Index Medicus, CRAC) and non-indexed literature systems were scanned and the pertinent manuscripts were annotated. Citation is by occurence in the literature so that historical trends may be viewed more easily. No analysis of the reference material is offered. Suggested however is that:
1. complications to cervical spine manipulation are being recognized and reported with increasing frequency,
2. a cause and effect relationship between stroke and cervical spine manipulation has not been established,
3. a screening mechanism that is valid, reliable and reasonable needs to be established.
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